This site is intended for general consumers in the United States of America.

Important Note: This information is intended to provide an overview of knee replacement surgery and should be reviewed with your doctor. It does not include all of the information needed to determine eligibility for knee replacement or for the proper use and care of artificial knee replacements. Please consult your surgeon for more information. Additional information may also be obtained by calling the toll-free number or visiting the web site below. Individual results may vary. Your results will depend on your personal circumstances. How long a knee replacement will last varies from patient to patient. It depends on many factors, such as the patient's physical condition, activity level, and body weight and the surgical technique. Replacement joints are not as strong or durable as natural, healthy joints, and there is no guarantee that a prosthetic joint will last the rest of a patient's life. All knee replacements may need to be replaced at some point.

All content herein is protected by copyright, trademarks and other intellectual property rights, as applicable, owned by or licensed to Zimmer Biomet or its affiliates unless otherwise indicated, and must not be redistributed, duplicated or disclosed, in whole or in part, without the express written consent of Zimmer Biomet.

For additional information or to find a doctor near you, visit or call 1-800-447-5633.

This device is available only on the order of a physician.

1. Total Knee Replacement [Internet]. American Academy of Orthopaedic Surgeons; 2009 April [cited 2011 Nov 20]. Available from:




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What Risks Are Involved?

While there are no guarantees, the complication rate following knee replacement is low. Serious complications, such as infection, can occur in approximately 2.0% of patients.1 Major medical complications, such as heart attack or stroke, occur even less frequently. Each of the following reactions or complications can occur during and after surgery and may require medical attention (such as further surgery and/or implant removal):

  • Blood clots
  • Bleeding
  • Slow wound healing
  • Infection
  • Allergic reaction to the knee implant components
  • Blood vessel damage
  • Nerve damage
  • Stiffness
  • Poor range of motion
  • Swelling and joint pain
  • Knee instability and/or dislocation
  • Loosening or fracture of the knee implant components
  • Bone fracture or break during surgery
  • Leg length discrepancy

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A Glimpse of Nancy Lopez's Journey Through Joint Pain

"Zimmer Biomet changed my life."

Nancy Lopez
Zimmer Biomet
Knee Implant recipient and paid endorser


The thought of never swinging a golf club again was unbearable for Nancy Lopez, a 48-time LPGA winning golfer. But that’s the tricky thing about pain... it can begin very mildly and progress over time until the mere act of standing is unbearable. 

Nancy Lopez hadn’t given up golf, but arthritic pain in her knees dampened her ability to play like she wanted. After 20 years of various treatments, Nancy could only stand for about 10 minutes before needing to sit. Getting all too comfortable with her couch, she was increasingly unable to perform the activities of daily living.

Like many people with chronic pain, Nancy began to experience discomfort in other areas of her body as well. This is called referred pain. By overcompensating for the pain in her knees, other areas of her body started to hurt. “It was horrible. Everything hurt,” Nancy said. “When I woke up, I had to mentally prepare myself for the pain. I felt like I was 100 years old.”

Nancy decided something had to be done. Under her doctor’s guidance, she began her treatment journey with less invasive options like medication, injections, and even stem cell treatments. While they provided short-term relief, Nancy eventually decided she needed to seek out other options.

She interviewed two orthopedic surgeons and chose one that best met her needs. After discussing her history of pain, Nancy and her doctor decided that a total knee replacement might provide the relief she was seeking.

In Nancy’s case, they were right. She was so pleased with the outcome of her first knee surgery that, right away, she knew she wanted the other knee done too. A year later, per her surgeon’s guidance, Nancy received her second total knee replacement.

Today, Nancy is back swinging her golf clubs, now with her grandchildren in tow. “Life is amazing,” Nancy said. “To not hurt anymore is just fantastic! I look forward to the rest of my life.”

If you have knee pain, talk to your surgeon to determine if surgery is right for you, and the risks of knee replacement surgery, including (but not limited to) infection, loosening, wear, bone or implant breakage, and pain, any of which may require additional surgery.

"I can swing a golf club again!"